Bromo-PEG1-Acid
- Product Name
- Bromo-PEG1-Acid
- CAS No.
- 1393330-33-0
- Chemical Name
- Bromo-PEG1-Acid
- Synonyms
- Bromo-PEG1-Acid;CAS_1393330-33-0;Br-PEG1-CH2CH2COOH;Bromo-PEG1-acid >=95%;Bromo-PEG1-propionic acid;3-(2-Bromoethoxy)propanoic acid;Propanoic acid, 3-(2-bromoethoxy)-
- CBNumber
- CB73062435
- Molecular Formula
- C5H9BrO3
- Formula Weight
- 197.03
- MOL File
- 1393330-33-0.mol
Bromo-PEG1-Acid Property
- storage temp.
- -20°C
- solubility
- DMSO : 100 mg/mL (507.54 mM; Need ultrasonic)
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 901573
- Product name
- Bromo-PEG1-acid
- Purity
- ≥95%
- Packaging
- 50MG
- Price
- $200
- Updated
- 2023/06/20
- Product number
- B800380
- Product name
- Bromo-PEG1-Acid
- Packaging
- 50mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- B800380
- Product name
- Bromo-PEG1-Acid
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- POL0002405
- Product name
- BROMO-PEG1-ACID
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $393.75
- Updated
- 2021/12/16
- Product number
- BIPG1321
- Product name
- Bromo-PEG1-Acid
- Packaging
- 100mg
- Price
- $428
- Updated
- 2021/12/16
Bromo-PEG1-Acid Chemical Properties,Usage,Production
Description
Bromo-PEG1-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bromo-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Bromo-PEG1-Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG1-Acid Suppliers
View Lastest Price from Bromo-PEG1-Acid manufacturers
- Product
- Br-PEG1-acid 1393330-33-0
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25